Home | Contact Us
SYNOPSIS FOR ROUND TWO GRANTS #2

SYNOPSIS OF AH&DMRT ROUND TWO RESEARCH GRANT #2

HYPERBARIC OXYGEN THERAPY FOR SUDDEN SENSORINEURAL HEARING LOSS

Investigators:

Associate Professor Michael Bennett MD FANZCA

Senior Staff Specialist

Department of Diving and Hyperbaric Medicine

Prince of Wales Hospital and the University of NSW

Tel: 02 9382 3880

Fax: 02 9382 3882

Email: m.bennett@unsw.edu.au

Dr. Thomas Kertesz MB BS, FRACS

Consultant Otorhinolaryngologist

Prince of Wales Hospital

Dr. Jan Lehm MD, FANZCA

Senior Staff Specialist

Dept. Diving and Hyperbaric Medicine

POWH and UNSW

Location:

This project will be undertaken at the Dept. Diving and Hyperbaric Medicine

Prince of Wales Hospital

Aim and hypothesis

We aim to test the hypothesis that hyperbaric oxygen therapy (HBOT), delivered in a timely fashion to patients with idiopathic sudden sensorineural hearing loss (ISSHL), will result in an improvement in both objective and functional hearing. Specifically, we wish to answer the clinical question:

"For adult patients presenting acutely with idiopathic sudden sensorineural hearing loss (with or without tinnitus), does the addition to therapy of hyperbaric oxygen result in clinically important improvements in hearing or tinnitus?"

Significance of this project

Sudden hearing loss is both common and of significant impact in the lives of those affected. At present there is no clear therapeutic option that results in a high proportion of those affected having a useful return of function. HBOT has been widely suggested as an appropriate therapeutic modality because of the well-documented ability to significantly raise tissue partial pressures of oxygen, even in the face of poor vascularity. A number of centres around the world already advocate the routine application of HBOT on the basis of some small but hopeful clinical trials. HBOT is particularly popular in Germany, Italy and Japan for example, although it is not routinely used in Australia.

If HBOT can be shown definitively to be associated with a useful clinical effect, this will be of great importance around the world. If, on the other hand, we can show that such a clinical effect is very unlikely, we can avoid future wasteful treatments and investigations for this condition.



Areas of Specialty
    Site Map | Privacy Statement |
 
Copyright 2017    Australasian Hyperbaric & Diving Medicine Research Trust
   Website by Michael Vaney Marketing